Endocrine Abstracts

Introduction: Primary adrenal lymphoma is extremely rare. It accounts for <1% of extranodal lymphoma. It affects typically old males with bilateral adrenal gland involvement that leads to adrenal hypofunction. Prognosis is very poor due to the lack of optimum chemotherapeutic regimens.Case Report: A 71 yearr old man with prior history of non insulin dependent diabetes, was admitted to the emergency department with symptoms of progressive weakness, fa...

Introduction: Pseudohypoparathyroidism (PHP) is a heterogeneous group of endocrine disorders characterized by target-organ resistance to the action of PTH, manifesting with hypocalcemia, hyperphosphatemia, and increased serum concentrations of PTH. PTH receptor couples with the stimulatory G protein (Gsα), leading to cAMP formation. Most cases of PHP are caused by heterozygous inactivating mutations in the GNAS gene, encoding Gs〈 (PHP type 1A) or methylatio...

Collision tumors (CT) refers to the coexistence of two histologically distinct malignant tumors within the same mass. CT involving the thyroid gland (TG) and/or the neck are specially uncommon and present a diagnostic and treatment challenge.Case report: A 69-year-old male presented with a one year history of bilateral cervical lymph node growth, a four-month history of progressive dysphagia and a dyspnea associated with a rapidly expanding, painless mas...

Riedel Thyroiditis is a rare form of infiltrative and fibrotic disease of the thyroid that is characterized by compressive symptoms resulting from a rapidly enlarging goiter. The association with Graves Thyroiditis and autoimmune diseases is very rare. The aim of this presentation is to report a patient with asymptomatic Riedel Thyroiditis associated with Thyroid Storm and Polyglandular Autoimmune Disease. A 54-year-old female patient with recent diagnosis of Grave’s Dise...

Thyroid storm (TS) is a rare and life threatening condition that requires a prompt recognition and treatment. The clinical features may overlap with other acute medical conditions. Currently both Akamizu Criteria (JTA) and Burch and Wartofsky Scale (BW) are helpful diagnostics tools.Objective: To evaluate TS patients according to currently available criteria and to identify the clinical features and outcomes.Methods: A single cente...

Thyroid storm (TS) is a rare but life-threatening manifestation of thyrotoxicosis.Objective: To describe the clinical features and outcomes of patients admitted for TS according to Burch-Wartofsky’s score (BW).Methods: A retrospective review of subjects admitted to a single hospital from 2009 through 2015 was conducted.Results: 15 cases were identified. Etiology: autoimmune (n=8), factitious (<e...

Background and aims: Periodontal disease (PD) is a chronic inflammatory condition where the key feature is the alveolar bone loss. Diabetes mellitus is a major risk factor in the occurrence of PD and vitamin D has been found to play a role in the development of diseases such as PD for its immunomoduratory and anti-inflammatory effects. The purpose of this study was to evaluate the relationship between PD and vitamin D levels in type 1 diabetic patients.S...

Introduction: Body composition is gaining great interest in some pathologies such as Type 1 Diabetes Mellitus (DM1). Adherence to the Mediterranean diet has been shown to be effective in improving the prognosis of cardiovascular disease, which is the main cause of mortality in these patients.Objectives: To assess whether adherence to the Mediterranean diet in DM1 is associated with improvement in disease control parameters, body composition, anthropometr...

Introduction: Islet hyperplasia and nesidioblastosis are described in the non neoplastic pancreas of patients with gastrinoma. It is not definately established whether hypergastrinemia can influence these changes. Moreover, rarely insulinoma and gastrinoma occur in the same patient but cases of single tumours cosecreting both insulin and gastrin have been described. Otherwise, the syndrome of hyperinsulinemic hypoglycaemia with nesidioblastosis after Roux-en-Y gastric bypass h...

Introduction: Diabetes mellitus is associated with an increased risk of osteoporotic fractures, which leads to an increased risk of disability and frailty.Aims: To assess the prevalence of frailty in type 2 diabetes and to analyze the relationship with bone mineral density (BMD) and Trabecular Bone Score (TBS), fracture risk and prevalent fractures.Methods: We carried out a cross-sectional study of 75 diabetic patients (65±7 y...